72 peptides · regulatory reference as of 2026 · not medical advice
If you’ve spent any time exploring the world of peptides, wellness optimization, or research compounds, you already know how fast the landscape moves. New compounds emerge constantly, scientific studies are published weekly, and regulatory guidelines shift beneath your feet.
For researchers, practitioners, and wellness enthusiasts alike, keeping track of what is legally permissible, what is under FDA review, what is flagged for safety, and what status a compound holds can feel like a full-time job.
That is precisely why Peptide Review Hub has put together this guide: to break down how to evaluate FDA regulatory statuses and bring clarity to a complex space.
10 - FDA Approved
6 - Compoundable
56 - Research Only
11 - Banned from Compounding
Name | Category | FDA Status | 503A Ban | Rx Required | Telehealth |
|---|---|---|---|---|---|
Pentadecapeptide BPC 157 | Healing & Recovery | Research Only | Yes | No | — |
Thymosin Beta-4 Fragment | Healing & Recovery | Research Only | Yes | No | — |
Copper Peptide GHK | Skin & Aesthetics | OTC Cosmetic | — | No | ✓ |
GHRH 1-29 | GH Secretagogues | FDA Approved | — | Yes | ✓ |
CJC-1295 DAC | GH Secretagogues | Compoundable | — | Yes | ✓ |
NNC 26-0161 | GH Secretagogues | Compoundable | — | Yes | ✓ |
Egrifta | GH Secretagogues | FDA Approved | — | Yes | ✓ |
Growth Hormone Releasing Peptide-6 | GH Secretagogues | Research Only | — | No | — |
Pralmorelin | GH Secretagogues | Research Only | — | No | — |
Examorelin | GH Secretagogues | Research Only | — | No | — |
Ozempic / Wegovy / Rybelsus | GLP-1 & Metabolic | FDA Approved | — | Yes | ✓ |
Mounjaro / Zepbound | GLP-1 & Metabolic | FDA Approved | — | Yes | ✓ |
LY3437943 | GLP-1 & Metabolic | Phase 3 | Yes | No | — |
HGH Fragment 176-191 | GLP-1 & Metabolic | Research Only | — | No | ✓ |
Victoza / Saxenda | GLP-1 & Metabolic | FDA Approved | — | Yes | ✓ |
Bremelanotide / Vyleesi | Sexual Health | FDA Approved | Yes | Yes | ✓ |
MT-II | Sexual Health | ⚠️ Not Approved — Caution | Yes | No | — |
Epitalon / Epithalamin | Longevity & Anti-Aging | Research Only | — | No | — |
Tα1 / Zadaxin | Immune Support | Compoundable (US) — Approved Internationally | — | Yes | ✓ |
Mitochondrial ORF of 12S rRNA type-c | Mitochondrial | Research Only | — | No | ✓ |
HN / Humanin-G (HNG) | Mitochondrial | Research Only | — | No | — |
Elamipretide / Szeto-Schiller Peptide 31 | Mitochondrial | Phase 3 | — | No | — |
Cathelicidin hCAP18 | Antimicrobial | Research Only | — | No | — |
α-MSH C-terminal tripeptide | Immune Support | Research Only | — | No | ✓ |
Vasoactive Intestinal Peptide | Immune Support | Compoundable | — | Yes | ✓ |
Dihexa PNB-0408 | Neurological & Cognitive | Research Only | — | No | — |
ACTH(4-10)-Pro-Gly-Pro | Neurological & Cognitive | Intl. Approved (Russia) | — | No | — |
Tuftsin Analog TP-7 | Neurological & Cognitive | Intl. Approved (Russia) | — | No | — |
Delta Sleep-Inducing Peptide | Neurological & Cognitive | Research Only | — | No | — |
Senolytic Peptide FOXO4 | Longevity & Anti-Aging | Research Only | — | No | — |
PEGylated Mechano Growth Factor | Healing & Recovery | Research Only | — | No | — |
Long R3 IGF-1 | GH Secretagogues | Research Only | — | No | — |
des(1-3)IGF-1 / Truncated IGF-1 | GH Secretagogues | Research Only — Preclinical Evidence | — | No | — |
Ramatercept / ActRIIB-Fc | Healing & Recovery | Research Only — Development Halted | — | No | — |
Human Growth Hormone / rhGH | Hormonal & Endocrine | FDA Approved (indication-specific) | — | Yes | ✓ |
Pitocin / Love Hormone | Hormonal & Endocrine | FDA Approved | — | Yes | ✓ |
GnRH / Factrel | Hormonal & Endocrine | FDA Approved / Compoundable | — | Yes | ✓ |
FST344 / Myostatin Inhibitor | Healing & Recovery | Research Only — Extreme Caution | — | No | — |
Cerebrolysin FPE 1070 | Neurological & Cognitive | Intl. Approved | — | No | — |
Nicotinamide Adenine Dinucleotide | Longevity & Anti-Aging | Supplement / Clinical Use | — | No | ✓ |
CJC-1295 (no DAC) / GRF 1-29 | GH Secretagogues | Research Only | — | No | — |
NNMT Inhibitor | GLP-1 & Metabolic | Research Only | — | No | — |
ERR Pan-Agonist | GLP-1 & Metabolic | Research Only | — | No | — |
Ibutamoren | GH Secretagogues | Research Only | — | No | — |
EDR Peptide | Longevity & Anti-Aging | Research Only | — | No | — |
Cartilage Bioregulator | Healing & Recovery | Research Only | — | No | — |
Ovarian Bioregulator | Hormonal & Endocrine | Research Only | — | No | — |
Adamax Semax-family Analog | Neurological & Cognitive | Research Only | — | No | — |
Cibinetide | Neurological & Cognitive | Investigational (Phase 2) | — | No | — |
Afamelanotide-related | Sexual Health | Caution: Indication-Specific Approval | — | Yes | — |
Pentosan Polysulfate PPS | Immune Support | FDA Approved / Other Indications | — | Yes | ✓ |
Kisspeptin-10 | Hormonal & Endocrine | Research Only | — | No | — |
Acetyl Octapeptide-3 | Skin & Aesthetics | OTC Cosmetic | — | No | — |
CagriSema Cagrilintide + Semaglutide | GLP-1 & Metabolic | Phase 3 | — | No | — |
AM833 | GLP-1 & Metabolic | Phase 3 Program | — | No | — |
Modified GRF 1-29 | GH Secretagogues | Research Only | — | No | — |
GSH | Longevity & Anti-Aging | Clinical / Compoundable | — | No | ✓ |
Larazotide AT-1001 | Healing & Recovery | Investigational | — | No | — |
Androxal | Hormonal & Endocrine | Investigational / Rx | — | Yes | ✓ |
Clomid | Hormonal & Endocrine | FDA Approved (indication-specific) | — | Yes | ✓ |
BPC-157 (Oral) Oral BPC-157 | Healing & Recovery | Research Only | Yes | No | — |
TB4 Fragment | Healing & Recovery | Research Only | Yes | No | — |
Nootropic Peptide Candidate | Neurological & Cognitive | Research Only | — | No | — |
RU-58841 RU58841 | Skin & Aesthetics | Research Only | — | No | — |
Collagen Peptides Hydrolyzed Collagen | Skin & Aesthetics | Supplement | — | No | — |
BPC-157 Stable BPC-157 Stable Capsule | Healing & Recovery | Research Only | Yes | No | — |
Levocarnitine | Longevity & Anti-Aging | Supplement / Rx forms | — | No | ✓ |
CDP-Choline Citicoline | Neurological & Cognitive | Supplement / Drug (region-dependent) | — | No | ✓ |
ITPP Myo-inositol trispyrophosphate | GLP-1 & Metabolic | Research Only | — | No | — |
Wolverine Blend Wolverine Stack · BPC-157 + TB-500 | Healing & Recovery | Research Only | Yes | No | — |
GLOW Stack · GHK-Cu + BPC-157 | Skin & Aesthetics | Research Only | Yes | No | — |
KLOW Stack · BPC-157 + TB-500 + GHK-Cu + KPV | Healing & Recovery | Research Only | Yes | No | — |
The Challenge: Information is Scattered and Complex
When looking into peptide regulations, users are usually met with a frustrating mix of:
Dense, legalistic FDA documentation and Federal Register notices.
Confusing distinctions between FDA-approved drugs, bulk compounding lists (Section 503A and 503B), and enforcement discretion policies.
Constantly shifting rules regarding safety categories and agency reviews.
Conflicting claims across forums, vendor marketing sites, and secondary blogs.
Deciphering whether a specific peptide can be legally compounded, whether it has active approvals, or where it stands on the regulatory radar shouldn't require a law degree. Yet, having clear, transparent access to this data is vital for anyone trying to stay informed and compliant.
Key Regulatory Frameworks to Watch
Understanding where a compound stands requires tracking a few core criteria:
FDA Approval Status: Distinguishing between fully FDA-approved pharmaceutical drugs, components of approved treatments, and non-approved research compounds.
Compounding & Bulk Substance Lists: Tracking positions under 503A/503B bulk drug substance lists, Category 1/Category 2/Category 3 designations, and interim enforcement policies.
WADA & Athletic Prohibitions: Highlighting compounds restricted or banned under competitive sport regulations.
Safety & Warning Signals: Monitoring official agency safety alerts, import alerts, and regulatory dockets.
Built for Education, Not Medical Advice
At Peptide Review Hub, our core philosophy centers around transparency, education, and objective evaluation.
This guide is designed purely as an educational resource to help you make sense of the regulatory landscape. It does not constitute medical, legal, or pharmaceutical advice, nor does it endorse, recommend, or encourage the use of any specific substance. Regulatory status is fluid, and decisions regarding health and treatment protocols should always be made in direct consultation with a licensed healthcare professional.