Peptide Review HubResearch Use Only. This compound is not intended for human consumption or therapeutic use.
Where to Buy Survodutide: Vendor Comparison & Research Info
Survodutide (BI-456906) is a synthetic 29-amino-acid peptide being studied as a dual GLP-1 receptor and glucagon receptor agonist. Its unique structure and extended-activity profile make it an area of interest in research involving glucose regulation, energy metabolism, body composition, and metabolic pathways. Supplied as a 10mg lyophilized powder, it is intended strictly for laboratory research use.
What is Survodutide?
Survodutide, also known as BI-456906, is a synthetic 29-amino-acid peptide being investigated as a dual agonist of the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR). Its dual-receptor activity makes it an important subject of research involving glucose regulation, energy metabolism, body composition, and metabolic disease.
The peptide incorporates a C18 diacid fatty-acid conjugate through a hydrophilic linker, a structural modification designed to extend its circulation time. It also contains the non-proteinogenic amino acid Ac4c (1-aminocyclobutane-1-carboxylic acid), which contributes to peptide stability.
Survodutide is supplied as a 10mg lyophilized powder intended for laboratory research. It is not intended for human or veterinary use.
Mechanism of Action
Survodutide is being studied for its simultaneous activity at GLP-1 and glucagon receptors. GLP-1 receptor signaling is associated with pathways involved in glucose-dependent insulin secretion, appetite regulation, and gastrointestinal activity, while glucagon receptor signaling is involved in energy expenditure, glucose metabolism, and lipid metabolism.
The dual mechanism provides researchers with an opportunity to investigate how coordinated GLP-1R and GCGR activation may influence metabolic pathways compared with selective activation of either receptor alone.
Chemical Identity
CAS Number: 2805997-46-8
Synonyms: BI-456906, EX-A7878, GTPL13383
Peptide Length: 29 amino acids
Molecular Formula: C₁₉₂H₂₈₉N₄₇O₆₁
Approximate Molecular Weight: 4,232 g/mol
Appearance: White to off-white lyophilized powder
Research Applications
Survodutide is being investigated across several areas of metabolic research, including:
GLP-1 receptor and glucagon receptor signaling
Glucose and energy metabolism
Appetite and metabolic regulation
Body-composition research
Lipid metabolism
Obesity and metabolic-disease models
Comparative research involving single- and dual-receptor agonists
Research findings should be interpreted within the context of the experimental model and should not be considered evidence of established clinical benefits.
Purity and Product Format
The product is supplied in a freeze-dried, lyophilized format intended to support peptide stability during storage. Purity and identity should be confirmed using the applicable batch-specific analytical documentation.
Where available, a Certificate of Analysis (CoA) can provide additional information regarding analytical testing, identity, purity, and batch specifications.
Key Features
Dual-Receptor Research: Investigates both GLP-1R and GCGR signaling pathways.
29-Amino-Acid Peptide: Engineered peptide structure incorporating the Ac4c residue.
C18 Diacid Conjugation: Lipid modification designed to influence peptide pharmacokinetic properties.
10mg Per Vial: Supplied as a lyophilized research formulation.
Research-Grade Format: Suitable for controlled laboratory and analytical research.
Lyophilized Stability: Freeze-dried presentation designed for appropriate laboratory storage.
Analytical Documentation: Batch-specific testing should be reviewed where provided.
Research-Use Disclaimer
For research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease or medical condition. Researchers are responsible for following applicable laboratory, regulatory, storage, handling, and disposal requirements.
Where to Buy Survodutide Online
| Rank | Vendor | Trust Score | Vial Size | Price / mg | Status | Action |
|---|---|---|---|---|---|---|
1 |  Peptide Hubs Verified | 9.0/10 Editorial Rating | $60.00 10mg vial | $6.00/mg | In Stock | Visit Site |
2 |  Dragon Peptides Verified | 9.0/10 Editorial Rating | $60.00 10mg vial | $6.00/mg | In Stock | Visit Site |
3 |  Dragon Pharma Store Verified | 9.0/10 Editorial Rating | $57.00 10mg vial | $5.70/mg | In Stock | Visit Site |
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Chemical Properties & Handling
Standard storage protocols for lyophilized peptides generally apply unless otherwise specified.
- Lyophilized (Powder): Store at -20°C for up to 3 years. Keep away from direct light and moisture.
- Reconstituted (Liquid): Store at 2-8°C (refrigerated) and use within 20-30 days to maintain stability.
Research Reviews
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