Research Use Only. This compound is not intended for human consumption or therapeutic use.
Where to Buy VIP: Vendor Comparison & Research Info
Research shows that VIP can help to reduce inflammation throughout the body, but that it is particularly useful in the setting of neurodegenerative disease, pulmonary fibrosis, inflammatory bowel disease, and cardiac fibrosis. The peptide appears to be highly effective in a number of fibrotic pathways and may offer treatment benefits in the common process of fibrosis that leads to so much morbidity and mortality. In addition to its antifibrotic effects, which appear to be mediated through anti-inflammatory actions, VIP is also a potent immune system regulator and general anti-inflammatory. The peptide has also been shown to protect the central nervous system against insult and is of active interest for its ability to preserve cognitive function in the setting of neurodegenerative disease.
What is VIP?
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.
Vasoactive Intestinal Peptide (VIP)
Vasoactive intestinal peptide (VIP, vasoactive intestinal polypeptide, PHM27) is a short peptide hormone made in the gut, pancreas, and brain of most vertebrate animals including humans. VIP binds to class II G protein-coupled receptors and is known to
VIP has long been an interest in research for all of the reasons above and more. There is a great deal of scientific literature on this particular peptide, making it nearly impossible to cover all of the many facets of VIP research. Below is a summary of some of the high points, including the most important aspect of VIP research – the finding that it VIP can reduce inflammation and fibrosis in a number of different organs.
VIP Peptide Structure
Amino Acid Sequence: HSDAVFTDNYXRLRKQMAVKKYLNSXLN Molecular Formula: C147H237N43O43S Molecular Weight: Human Gene: VIP; 6q25.2 PubChem CID: 44567960 CAS Number: 37221-79-7 Synonyms: VIP, PHM27, Vasoactive intestinal polypeptide
VIP Research
Bowel Inflammation
As it turns out, one of the primary producers of VIP is the immune nerve fibers in blood vessels of the central and peripheral nervous systems and heart. Additionally, VIP is produced directly by cells of the immune system where it helps to promote Th2-type responses which can reduce inflammation and quiet the immune system. VIP and analogues derived from it have been heavily investigated as potential inflammatory mediators in intestinal disease, heart disease, and neuroinflammatory conditions[1], [2].
The various roles of VIP in immunomodulation:
In the setting of inflammatory bowel diseases (IBDs) like Crohn’s and ulcerative colitis, VIP has been found to improve intestinal barrier homeostasis and reduce inflammation driven by Th1 cell actions[3]. This latter approach, in particular, appears to generate T cells capable of producing the inflammation suppressing peptide interleukin-10[4]. In recent years it has become apparent that Th1 inflammation is one of several important pathways in IBD.
The benefit of improved intestinal barrier function should not be understated as it is hypothesized to be a contributing cause in the pathogenesis of inflammatory bowel disease. In particular, it is thought that compromised barrier function leads to increased antigenic material in the space between cells where it is more likely to interact with immune cells and set off an inflammatory response. Mitigating antigen presentation to immune cells via improved barrier function secondary to VIP would thus reduce what is believed to be one of the first steps in the cascade of events leading to colitis and severe inflammatory bowel disease[3].
Vasoactive Intestinal Peptide in Lung Function
There are at least two ways in which VIP impacts lung function. In the first mechanism, VIP modulates pulmonary vascular remodeling in response to inflammation. It appears to have this effect though suppression of a peptide call NFAT, which activates T cells and leads to increased inflammation[5]. Consistent with its roll in modulating inflammation in other tissues, VIP appears to control T-cell mediate inflammation in the lungs, a process that heretofore has been difficult to address in models of inflammation. In particular, NFAT suppression may play a very important role in preventing pulmonary fibrosis, the end stage of a number of inflammatory conditions such as COPD, sarcoidosis, etc[6]. Thus, VIP may provide a very useful mechanism for preventing the kind of end stage lung disease that can only be cured by transplant and which often results in serious morbidity and even death.
VIP also appears to inhibit the proliferation of smooth muscles in pulmonary tissue. Smooth muscle cell proliferation is one of the long-term consequences of lung inflammation and is a particular problem in bronchial asthma that has been uncontrolled for extended periods[7]. There is hope that VIP will provide a mechanism by which to mitigate the effects of long-term inflammation secondary to asthma.
There is also exceptional evidence that the vasodilatory effects of VIP, which are known to help control blood pressure, may have a highly potent effect in pulmonary vasculature. Preliminary research shows that VIP lowers blood pressure significantly in the pulmonary artery, leading to increased cardiac output and improved venous oxygen saturation[8]. While more work remains to be done, there is significant hope that VIP will offer a new modality for improving lung function in the setting of primary vascular conditions.
VIP in Transplants
One of the primary problems with organ transplants is rejection by the body’s immune system. No matter how good the match between donor and recipient, the body mounts a response against transplanted organs that eventually leads to their destruction and failure. Currently, the only solution to this problem is the use of broad-spectrum anti-inflammatory medications. Unfortunately, these drugs can lead to susceptibility to serious infections and have side effects of their own, such as scarring and organ fibrosis, that can limit their use.
Research on VIP has revealed that the peptide affects dendritic cells (DCs). DCs are important in the immune response because they help the body to recognize antigens and mount appropriate countermeasures. By reducing DC proliferation and activation, VIP helps to thwart immune responses before they are even mounted. Interestingly, this function seems to favor DCs attached to antigens that are tolerogenic. In other words, VIP selectively inhibits the proliferation of DCs that might cause an autoimmune reaction. This is an area of active research as VIP could potentially reduce transplant rejection with fewer infection-promoting side effects[9]. This could make VIP or an analogue of it the foundation of transplant anti-rejection medicine in the future.
VIP as a Neuroprotectant
The role of VIP in the central nervous system is threefold: neurotransmitter, neurotrophic/neurogenic, and anti-inflammatory/neuroprotectant. As with the intestine, VIP’s role in the CNS begins with maintaining barriers. In this case, the peptide helps to maintain the very critical function of the blood-brain barrier (BBB)[10]. The BBB is a layer of cellular protection between blood vessels and the tissue of the central nervous system. It regulates what enters neurological tissue and thus controls everything from nutrition and oxygenation to immune function. Compromise of the BBB has been implicated in the pathophysiology of multiple sclerosis, encephalomyelitis, and even stroke.
VIP has also been shown to regulate the accumulation of beta amyloid in mouse models of Alzheimer’s disease and is known to offer neuroprotective effects in Parkinson’s disease[11], [12]. There is also evidence that VIP is an important neuroprotectant in the developing brain where it helps to ward of excitotoxic white matter damage and improve neuron fatty acid myelination[13]. In the case of Parkinson’s disease, VIP appears to offer a similar benefit as in other inflammatory settings by shifting the immune balance away from inflammatory Th1 responses toward anti-inflammatory Th2 responses[14].
The exact role of VIP in Alzheimer’s disease (AD) is less clear. Research shows that processing of VIP is inhibited in AD with levels of the peptide as well as amino acid byproducts being lower in the brains of people affected by AD[15], [16]. Again, the research is unclear at this point, but infusion of VIP into the brains of mice shows a substantial reduction in beta amyloid levels, proving that the peptide plays an important role in the pathophysiology of the disease.
The effects of VIP in protecting the CNS appear to be mediated through VPAC1 and VPAC2 receptors. In both cases, stimulation appears to result in increased secretion of neurotrophic factors like ADNP (activity-dependent neurotrophic factor) and BDNF (brain-derived neurotrophic factor). Both of these peptides help to protect synapses and astrocytes.
Cardiac Fibrosis
As with lung disease, fibrosis is the end stage of a number of different heart conditions. Cardiac fibrosis leads to a number of serious problems including valve dysfunction, decreases in contractility, changes in cardiac filling, and electrical problems. As in lung disease, cardiac fibrosis is the common end stage of many heart conditions and generally necessitates transplant in order to avoid mortality.
To date, most cardiac research has focused on preventing scar formation from occurring. A number of commonly used drugs can, at least to some extent, help to slow the process of cardiac remodeling that leads to scarring. Unfortunately, very few cases are 100% successful and most people experience progressive fibrosis and decline in cardiac function. Recent research in rats, however, indicates that VIP may not only slow fibrosis down, but can reverse scarring. It appears that at least part of this effect is mediated through a massive reduction in angiotensinogen and angiotensin receptor type 1a expression. This makes sense as angiotensin receptor blockers and ACE inhibitors have long been known to slow down cardiac modeling/fibrosis and are in fact the first line of prevention for fibrosis[17].
Vasoactive Intestinal Peptide and COVID 19
An interesting recent development out of Switzerland and the United States indicates that a synthetic version of VIP called aviptadil (RLF-100) may help to alleviate the lung complications in severe cases of Covid 19. Aviptadil, like VIP, inhibits pro-inflammatory cytokine production. In the lungs, this translates into protection of type-2 alveolar cells, the cells responsible for the bulk of oxygen exchange that takes place in the lungs. In fact, it appears that Aviptadil may actually prevent the SARS-2 coronavirus from penetrating these cells and infecting them. There are currently ongoing phase 2/3, placebo-controlled trials to investigate the effectiveness of this VIP derivative in protecting against serious complications of COVID 19[18].
According to Dr. Jonathan Javitt, CEO of NeuroRX (NeuroRX has paired with the maker of aviptadil to expedite development and use of the drug in the treatment of COVID), rapid recovery is seen in patients on ventilators and ECMO just three days after treatment with RLF-100. This is even that case in patients with severe medical comorbidities. The drugs has been administered on an emergency basis to patients too ill to be admitted to the clinical trial. Dr. Javitt points out that no antiviral agent has demonstrated the kind of rapid recovery from infection and demonstrated inhibition of viral replication the way that Aviptadil has.
Vasoactive Intestinal Peptide and COVID 19
VIP is a member of a much larger group of neuro and endocrine peptides. It has been shown to have a number of effects in relation to the central nervous system, GI tract, pulmonary tissue, and immune system. It is known to play an active role in embryonic growth and development.
Research shows that VIP can help to reduce inflammation throughout the body, but that it is particularly useful in the setting of neurodegenerative disease, pulmonary fibrosis, inflammatory bowel disease, and cardiac fibrosis. The peptide appears to be highly effective in a number of fibrotic pathways and may offer treatment benefits in the common process of fibrosis that leads to so much morbidity and mortality.
In addition to its antifibrotic effects, which appear to be mediated through anti-inflammatory actions, VIP is also a potent immune system regulator and general anti-inflammatory. The peptide has also been shown to protect the central nervous system against insult and is of active interest for its ability to preserve cognitive function in the setting of neurodegenerative disease.
Finally, synthetic versions of VIP have shown promise in treating COVID 19 and have been fast-tracked by the FDA for stage 2/3 clinical trials. This may ultimately prove beneficial for other VIP-related treatments as evidence from successful clinical trials can help to inform future clinical trials and provide pharmaceutical companies with incentive to pursue therapeutics that have an increased potential of being approved for use in humans. The next decade is likely to bring a great deal of innovation and research to vasoactive intestinal peptide.
VIP exhibits minimal side effects, low oral and excellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale to humans. VIP for sale at peptide Review hub is limited to educational and scientific research only, not for human consumption. Only buy VIP if you are a licensed researcher.
Article Author
The above literature was researched, edited and organized by Dr. E. Logan, M.D. Dr. E. Logan holds a doctorate degree from Case Western Reserve University School of Medicine and a B.S. in molecular biology.
Where to Buy VIP Online
| Rank | Vendor | Trust Score | Vial Size | Price / mg | Status | Action |
|---|---|---|---|---|---|---|
1 | 9.3/10 Editorial Rating | $49.99 10mg vial | $5.00/mg | In Stock | Visit Site | |
2 |  Peptide Hubs Verified | 9.0/10 Editorial Rating | $50.00 6mg vial | $8.33/mg | Out of Stock | Visit Site |
3 |  Dragon Peptides Verified | 9.0/10 Editorial Rating | $50.00 10mg vial | $5.00/mg | Out of Stock | Visit Site |
4 | 7.8/10 Editorial Rating | $29.99 114mg vial | $0.26/mg | In Stock | Visit Site | |
5 |  Pure Peptide Labs Verified | 5.0/10 Editorial Rating | $59.95 10mg vial | $6.00/mg | In Stock | Visit Site |
6 |  Core Peptides Verified | 4.0/10 Editorial Rating | $64.00 6mg vial | $10.67/mg | In Stock | Visit Site |
7 | N/A/10 Editorial Rating | $85.00 10mg vial | $8.50/mg | In Stock | Visit Site | |
8 | N/A/10 Editorial Rating | $59.00 10mg vial | $5.90/mg | In Stock | Visit Site | |
9 | N/A/10 Editorial Rating | $69.00 5mg vial | $13.80/mg | In Stock | Visit Site | |
10 | N/A/10 Editorial Rating | $500.00 10mg vial | $50.00/mg | In Stock | Visit Site | |
11 | N/A/10 Editorial Rating | $249.00 10mg vial | $24.90/mg | In Stock | Visit Site | |
12 | N/A/10 Editorial Rating | $89.99 10mg vial | $9.00/mg | In Stock | Visit Site | |
13 | N/A/10 Editorial Rating | $59.00 6mg vial | $9.83/mg | In Stock | Visit Site | |
14 | N/A/10 Editorial Rating | $465.00 10mg vial | $46.50/mg | In Stock | Visit Site | |
15 | N/A/10 Editorial Rating | $59.99 10mg vial | $6.00/mg | In Stock | Visit Site | |
16 | N/A/10 Editorial Rating | $58.00 10mg vial | $5.80/mg | In Stock | Visit Site | |
17 | N/A/10 Editorial Rating | $110.00 10mg vial | $11.00/mg | In Stock | Visit Site | |
18 | N/A/10 Editorial Rating | $381.21 25mg vial | $15.25/mg | In Stock | Visit Site | |
19 | N/A/10 Editorial Rating | $79.00 10mg vial | $7.90/mg | In Stock | Visit Site |
Top-Ranked Vendor
Overall Score
Category Scores
COA Transparency: 8.5/10
Reputation: 8.0/10
Pricing: 9.0/10
Policies: 8.0/10
Shipping: 8.5/10
Catalog: 9.5/10
Overall Score: 8.6/10
Calculation
(8.5 + 8.0 + 9.0 + 8.0 + 8.5 + 9.5) ÷ 6 = 8.58/10
COA Transparency
Score: 8.5/10
Analysis
Soma Chems places significant emphasis on product verification and quality assurance. The company promotes third-party testing and indicates that products are supported by Certificates of Analysis (COAs). Public information suggests that laboratory testing includes purity verification and analytical review of products before release.
The supplier also highlights quality-tested research compounds and publishes documentation supporting product verification. Compared with many research-peptide vendors, Soma Chems demonstrates a stronger commitment to transparency by referencing laboratory testing and quality-control procedures throughout its catalog.
However, the depth and consistency of publicly available COA documentation appear to vary among products. A larger archive of standardized batch-specific reports and easier access to historical testing data would further improve transparency.
Overall, Soma Chems performs well in this category and demonstrates an above-average focus on quality verification.
Reputation
Score: 8.0/10
Analysis
Soma Chems has established a growing reputation within the research-peptide industry and has received positive attention from several peptide-review platforms. Customer feedback commonly highlights fast shipping, competitive pricing, product quality, and responsive customer service.
Available reviews often praise the overall purchasing experience, reliable product availability, and communication during the ordering process. Several customers also reference repeat purchases and positive long-term experiences with the company.
Although the company does not yet have the same level of mainstream recognition as the largest peptide suppliers, its reputation profile appears to be steadily improving. Some customers have reported occasional shipping delays, but these complaints appear relatively limited compared with the volume of positive feedback.
Overall, Soma Chems maintains a positive reputation and favorable customer sentiment.
Pricing
Score: 9.0/10
Analysis
Pricing is one of Soma Chems' strongest competitive advantages. The supplier offers a large selection of peptides, sprays, amino products, blends, and specialty research compounds at pricing that is frequently lower than many premium competitors.
The company appears particularly focused on affordability without sacrificing product diversity. In addition to traditional peptide formats, Soma Chems offers oral formulations, sprays, and specialty blends that help differentiate its inventory from many competing suppliers.
Discounts, promotional offers, and value-oriented pricing further contribute to the company's appeal. Researchers seeking broad product availability at accessible pricing levels may find Soma Chems particularly attractive.
Overall, Soma Chems delivers excellent value for money and performs exceptionally well in the pricing category.
Policies
Score: 8.0/10
Analysis
Soma Chems provides clear research-use disclaimers and explains that its products are intended exclusively for analytical and scientific research purposes. The company also communicates that it is not a compounding pharmacy and provides policy information regarding privacy and data handling.
The supplier maintains accessible customer-service channels and basic ordering information, helping customers understand purchasing requirements and product restrictions.
While the company demonstrates above-average policy transparency compared with many peptide vendors, additional public detail regarding returns, refunds, exchanges, and shipment claims would strengthen the customer experience further.
Overall, policy information is professional, clear, and suitable for research-focused customers.
Shipping
Score: 8.5/10
Analysis
Shipping is frequently cited as a strength of the Soma Chems operation. Customer feedback often highlights fast fulfillment, prompt delivery, and reliable order processing.
The company appears focused on maintaining customer satisfaction through efficient shipping workflows and responsive communication. Review-platform feedback suggests that most customers experience timely deliveries and accurate order fulfillment.
Although isolated complaints regarding delayed shipments exist, they appear to represent exceptions rather than common experiences. The company also benefits from straightforward payment options that can simplify the ordering process for many customers.
Overall, shipping performance appears reliable and supports a positive customer experience.
Catalog
Score: 9.5/10
Analysis
Catalog depth is one of Soma Chems' most impressive strengths. The company offers more than 100 research products spanning peptides, amino compounds, sprays, liquids, blends, and specialty formulations.
Recovery and Regenerative Peptides
Examples
BPC-157
TB-500
GHK-Cu
LL-37
Growth and Performance Peptides
Examples
CJC-1295
Ipamorelin
Tesamorelin
IGF-LR3
Metabolic Research Compounds
Examples
AOD-9604
MOTS-C
Cagrilintide
Weight-management blends
Cognitive Research Compounds
Examples
Semax
Selank
Pinealon
P21
Specialty Products
Examples
Sprays
Amino formulations
Multi-peptide blends
NAD+
Melanotan products
The combination of variety, organization, and specialty offerings makes Soma Chems one of the broader catalogs currently available within this market segment.
What We Like
Positive Highlights
Large peptide and research-compound catalog.
Third-party testing emphasis.
COA availability.
Competitive pricing.
Strong product diversity.
Positive customer feedback.
Fast shipping reputation.
Availability of sprays and alternative formulations.
What Could Be Better
Areas for Improvement
More consistent public COA documentation.
Expanded historical testing archives.
Greater transparency regarding laboratory partners.
More detailed refund and return policies.
Increased mainstream review-platform presence.
Additional educational content for new researchers.
Online Ratings & Reviews
Trustpilot
Rating
Information Not Publicly Available.
Review Count
Information Not Publicly Available.
Key Positive Themes
Information Not Publicly Available.
Key Negative Themes
Information Not Publicly Available.
Finnrick
Rating
Information Not Publicly Available.
Key Findings
No verified Finnrick rating identified.
Limited supplier-specific analytical coverage available.
Notable Observations
Independent review activity is stronger on peptide-focused platforms.
Other Review Sources
Peptide Review Platforms
Rating
Approximately 4.7/5
Review Count
More than 20 publicly available reviews.
Key Findings
Positive comments regarding product quality.
Frequent praise for shipping speed.
Strong customer-service feedback.
Competitive pricing repeatedly highlighted.
Vendor Analysis Platforms
Key Findings
Large product inventory.
Competitive market positioning.
Strong value-oriented approach.
Broad availability of oral and spray formulations.
Community Discussions
Key Findings
Positive reception for affordability.
Appreciation for product diversity.
Growing visibility within the peptide community.
Overall Public Sentiment
Most Common Praise
Fast shipping.
Competitive pricing.
Product quality.
Large inventory.
Responsive customer support.
Easy ordering process.
Most Common Complaints
Occasional shipping delays.
Variability in COA depth.
Limited mainstream review coverage.
Relatively modest brand recognition compared with industry leaders.
Public Sentiment Summary
Overall sentiment is positive. Customers frequently praise Soma Chems for affordability, shipping speed, product availability, and quality. Most criticisms are relatively minor and relate to transparency enhancements or isolated logistical issues rather than product concerns.
Brand Overview
Company Name
Soma Chems
Website
Industry
Research Peptides and Research Compounds
Main Products
BPC-157
TB-500
GHK-Cu
CJC-1295
Ipamorelin
Tesamorelin
AOD-9604
MOTS-C
Semax
Selank
Pinealon
Melanotan products
Headquarters
Information Not Publicly Available
Shipping Regions
Information Not Publicly Available
Payment Methods
Credit Cards
Company Summary
Soma Chems is a research-peptide supplier focused on providing peptides, amino products, sprays, liquids, blends, and specialty research compounds. The company has developed a reputation for combining product diversity with competitive pricing, making it attractive to researchers seeking a broad range of compound options.
One of the company's strongest assets is its extensive catalog, which spans metabolic peptides, regenerative compounds, cognitive products, performance-focused peptides, and specialty formulations. The availability of sprays and alternative delivery formats further differentiates the supplier from many competitors.
Soma Chems also emphasizes quality verification through third-party testing and COA-supported products. These initiatives contribute positively to transparency and customer confidence. Customer reviews frequently highlight reliable fulfillment, affordable pricing, and responsive support.
While the company could strengthen transparency through a more extensive public archive of laboratory reports, it already provides many of the trust signals researchers seek when evaluating suppliers.
Overall, Soma Chems presents a strong profile supported by broad inventory depth, favorable pricing, quality-focused operations, and positive customer sentiment.
Final Verdict
Is Soma Chems Worth Considering?
Soma Chems appears best suited for researchers seeking a supplier that combines affordability, inventory depth, and product variety. The company's strongest advantages include competitive pricing, a large peptide catalog, positive customer feedback, and a growing reputation within the research-compound market.
The supplier performs especially well in categories related to product selection and value. Researchers can access a diverse range of compounds, including popular peptides, specialty blends, cognitive compounds, sprays, and amino-based formulations. This breadth makes the platform appealing for buyers who prefer sourcing from a single vendor.
Quality assurance also contributes positively to the company's profile. The supplier promotes laboratory testing and COA-backed products, helping support confidence in product quality and consistency. Customer feedback further reinforces strengths related to fulfillment and customer service.
The primary opportunities for improvement involve expanding public testing archives and providing greater transparency regarding laboratory partners and quality-control practices.
Overall, Soma Chems presents a positive profile characterized by excellent product diversity, strong value, and a growing reputation for quality and service. For many research-focused buyers, it represents a competitive option within the peptide marketplace.
Final Verdict Score: 8.6/10
Chemical Properties & Handling
Standard storage protocols for lyophilized peptides generally apply unless otherwise specified.
- Lyophilized (Powder): Store at -20°C for up to 3 years. Keep away from direct light and moisture.
- Reconstituted (Liquid): Store at 2-8°C (refrigerated) and use within 20-30 days to maintain stability.
Research Reviews
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Best VIP Vendors & Price Comparison
Vasoactive Intestinal Peptide (VIP) is a naturally occurring neuropeptide and peptide hormone widely studied in immunology, neuroscience, gastrointestinal physiology, pulmonary biology, cardiovascular research, and inflammation science. Researchers investigate VIP because of its relationship with immune regulation, tissue homeostasis, neuroprotection, vascular function, and anti-inflammatory signaling pathways.
As interest in neuroimmune and anti-inflammatory peptide research continues to grow, researchers frequently compare VIP suppliers based on purity, analytical testing, manufacturing standards, pricing, and supplier transparency.
This VIP Vendor Price Comparison Guide helps researchers evaluate suppliers using objective criteria including:
Product Pricing
Cost Per Milligram
Product Purity
Third-Party Testing
Certificate of Analysis (COA)
Vendor Reputation
Customer Reviews
Shipping Performance
Product Availability
Overall Value
Whether you're searching for the lowest-priced VIP supplier, the highest-purity research-grade material, or vendors offering extensive analytical verification, this guide provides a framework for comparing research peptide suppliers.
Explore VIP Vendors by Criteria
Most Popular VIP Vendors
Compare suppliers frequently selected by immunology, neuroscience, and inflammation researchers.
Highest Reviewed VIP Vendors
Discover peptide suppliers with strong customer satisfaction and positive marketplace reputations.
Lowest Price VIP Vendors
Identify suppliers offering competitive pricing and attractive cost-per-milligram value.
Highest Purity VIP Vendors
Review suppliers providing transparent purity verification and laboratory testing.
Best Value VIP Vendors
Compare pricing, testing standards, documentation quality, and customer support.
Fastest Shipping VIP Vendors
Evaluate shipping reliability, package handling, and fulfillment speed.
Newly Listed VIP Vendors
Explore recently added suppliers offering VIP research peptides.
What Is VIP?
Overview
Vasoactive Intestinal Peptide (VIP) is a naturally occurring peptide hormone produced in the gastrointestinal tract, pancreas, central nervous system, and peripheral nervous system.
Researchers investigate VIP because of its relationship with:
Immune-system regulation
Neuroprotection
Gastrointestinal physiology
Pulmonary function
Vascular biology
Inflammatory signaling
Tissue homeostasis
Cellular communication
VIP remains one of the most extensively studied neuroimmune peptides in biomedical research.
Molecular Characteristics
Peptide Information
Researchers evaluating VIP products should carefully review analytical documentation and molecular specifications.
Peptide Name
Vasoactive Intestinal Peptide (VIP)
Alternative Names
VIP
Vasoactive Intestinal Polypeptide
PHM27
Classification
Neuropeptide & Peptide Hormone
Research Category
Immunology, Neuroscience & Inflammation Research
Human Gene
VIP (6q25.2)
Amino Acid Sequence
HSDAVFTDNYXRLRKQMAVKKYLNSXLN
Molecular Formula
C147H237N43O43S
PubChem CID
44567960
CAS Number
37221-79-7
Product Format
Lyophilized Peptide Preparation
Why Researchers Study VIP
VIP has generated significant scientific interest because of its widespread biological activity across multiple organ systems.
Researchers investigate pathways involving:
Immune signaling
Cytokine regulation
Neuroprotection
Barrier integrity
Anti-inflammatory communication
Fibrosis-associated pathways
Its broad physiological role makes VIP one of the most versatile peptides in modern research.
VIP & Immune-System Research
Immune Modulation
One of the primary areas of VIP research involves immune-system regulation.
Researchers investigate pathways involving:
T-cell signaling
Cytokine production
Immune communication
Inflammatory regulation
Cellular immune responses
This remains one of the largest areas of scientific investigation.
Anti-Inflammatory Research
Researchers continue studying pathways involving:
Immune balance
Inflammatory mediators
Cytokine signaling
Cellular adaptation
Tissue-protective responses
Further studies remain ongoing.
VIP & Gastrointestinal Research
Intestinal Barrier Research
VIP is widely studied because of its relationship with gastrointestinal physiology.
Researchers investigate pathways involving:
Intestinal barrier integrity
Gut-cell communication
Mucosal maintenance
Inflammatory signaling
Gastrointestinal homeostasis
These pathways remain central to VIP research.
Inflammatory Bowel Disease Research
Scientists continue examining pathways involving:
Intestinal inflammation
T-cell activity
Immune regulation
Barrier function
Cytokine biology
Further investigation remains ongoing.
VIP & Pulmonary Research
Lung Function Research
Researchers investigate VIP because of its relationship with pulmonary physiology.
Research includes pathways involving:
Pulmonary signaling
Respiratory-system regulation
Airway biology
Vascular adaptation
Lung-tissue communication
This remains a rapidly expanding area of study.
Pulmonary Fibrosis Research
Scientists continue studying mechanisms involving:
Fibrosis-associated signaling
Tissue remodeling
Inflammatory regulation
Cellular adaptation
Lung-tissue maintenance
Further investigations remain active.
Pulmonary Vascular Research
Researchers examine pathways involving:
Pulmonary circulation
Vascular relaxation
Endothelial signaling
Blood-flow regulation
Respiratory physiology
Additional studies continue in this field.
VIP & Neurological Research
Neuroprotection Research
VIP has generated significant interest in neuroscience because of its relationship with:
Neuronal survival
Brain-cell communication
Neuroimmune regulation
Synaptic maintenance
Cellular resilience
This remains a major area of scientific investigation.
Blood-Brain Barrier Research
Researchers investigate pathways involving:
Barrier integrity
Neural protection
Cellular communication
Neurovascular regulation
Central nervous system homeostasis
Further research remains ongoing.
Neurodegenerative Disease Research
Scientists continue studying pathways involving:
Brain aging
Neuroinflammation
Cognitive function
Cellular adaptation
Neuronal signaling
Additional investigations continue expanding understanding in this field.
Alzheimer's Disease Research
Research involving VIP frequently examines:
Amyloid-associated pathways
Cognitive resilience
Neuronal communication
Neuroprotective signaling
Brain-cell maintenance
This remains an active area of interest.
Parkinson's Disease Research
Researchers investigate pathways involving:
Neuroimmune communication
Neuronal resilience
Inflammatory signaling
Cellular protection
Brain physiology
Further studies remain ongoing.
VIP & Cardiovascular Research
Vascular Biology Research
VIP remains an important peptide in vascular research.
Researchers investigate pathways involving:
Blood-vessel communication
Endothelial function
Vascular adaptation
Circulatory physiology
Hemodynamic regulation
Cardiac Fibrosis Research
Scientists continue exploring pathways involving:
Fibrotic signaling
Tissue remodeling
Cellular communication
Cardiovascular adaptation
Structural maintenance
Research remains active in this area.
Blood Pressure Research
Researchers also investigate relationships involving:
Vascular relaxation
Circulatory-system regulation
Endothelial signaling
Cardiovascular communication
Physiological homeostasis
VIP & Transplant Research
Immune Tolerance Research
VIP has also been studied for its influence on:
Dendritic-cell biology
Immune recognition
Cellular communication
Immune adaptation
Tolerance-associated pathways
These remain important areas of modern immunology research.
Why Researchers Compare VIP Vendors
Research reproducibility depends heavily on peptide quality and manufacturing consistency.
Differences among suppliers may include:
Product purity
Batch consistency
Stability testing
Manufacturing standards
Storage procedures
Analytical verification
Product documentation
Quality-control systems
Careful supplier selection helps improve consistency and reliability across research studies.
How We Compare VIP Vendors
Third-Party Laboratory Testing
Independent testing remains one of the strongest indicators of peptide quality.
Researchers should prioritize suppliers offering:
Third-party laboratory testing
Identity verification
Purity confirmation
Batch-specific reports
Certificate of Analysis (COA)
A quality COA should contain:
Batch number
Testing date
Purity percentage
Identity verification
Analytical methodology
Product Purity
Purity remains one of the most important variables when evaluating research peptides.
Higher-purity products generally contribute to improved reproducibility and experimental consistency.
Cost Per Milligram
Comparing vial prices alone may not accurately reflect overall value.
Cost Per Milligram Formula
Product Price ÷ Total Milligrams = Cost Per Milligram
This metric helps standardize supplier comparisons.
Customer Reviews
Customer experiences often provide insight regarding:
Product consistency
Packaging quality
Shipping reliability
Customer support
Purchasing experience
Vendor Reputation
Established suppliers often demonstrate:
Transparent testing standards
Reliable quality-control procedures
Consistent inventory availability
Strong customer satisfaction
Product Quality & Analytical Testing
Why Testing Matters
Research-grade VIP products should undergo testing to verify:
Identity
Purity
Stability
Composition
Batch consistency
Common Testing Methods
High-Performance Liquid Chromatography (HPLC)
Used to evaluate purity and identify impurities.
Mass Spectrometry (MS)
Used to verify molecular identity and composition.
Identity Verification Testing
Confirms peptide authenticity.
Stability Testing
Measures peptide integrity during storage.
Batch Consistency Testing
Evaluates reproducibility across manufacturing lots.
Understanding VIP Pricing
Several factors influence supplier pricing.
Product Purity
Higher-purity products often command premium pricing.
Complex Manufacturing
VIP is a relatively large peptide requiring advanced synthesis and purification procedures.
Analytical Verification
Comprehensive testing programs improve transparency while increasing production costs.
Research Demand
Growing interest in neuroimmune and anti-inflammatory research contributes to market demand.
Vendor Reputation
Established suppliers often command higher pricing due to rigorous quality-assurance standards.
VIP Vendor Evaluation Checklist
Quality Verification
✅ Third-party testing available
✅ Certificate of Analysis provided
✅ Identity verification documented
✅ Purity information disclosed
✅ Batch-specific testing available
✅ Stability information available
Vendor Reliability
✅ Positive customer reviews
✅ Transparent company information
✅ Responsive customer support
✅ Reliable inventory availability
Purchasing Experience
✅ Secure checkout process
✅ Shipment tracking available
✅ Clear refund policies
✅ Reliable order fulfillment
Red Flags When Comparing Vendors
Testing Concerns
❌ No third-party testing
❌ Missing COAs
❌ Unverified purity claims
❌ Missing identity verification
❌ Outdated laboratory reports
Transparency Issues
❌ Hidden specifications
❌ Missing batch information
❌ Limited analytical documentation
❌ No supplier contact information
Service Problems
❌ Frequent inventory shortages
❌ Poor communication
❌ Negative customer reviews
❌ Unclear shipping policies
Frequently Asked Questions
What is VIP?
VIP (Vasoactive Intestinal Peptide) is a naturally occurring neuropeptide and peptide hormone investigated for its role in immune regulation, inflammation biology, gastrointestinal physiology, pulmonary function, and neuroprotection.
What is VIP used for in research?
Researchers investigate VIP in studies involving inflammatory bowel disease, pulmonary biology, fibrosis pathways, neurodegenerative disease, immune regulation, cardiovascular physiology, and transplant-related immune responses.
Why compare VIP vendors?
Purity, analytical testing, supplier reliability, pricing, and documentation quality can vary significantly among peptide vendors.
What should researchers review before purchasing?
Researchers should evaluate:
Certificate of Analysis (COA)
Third-party laboratory testing
Purity verification
Identity confirmation
Vendor reputation
Customer reviews
Why is third-party testing important?
Independent testing helps verify peptide identity, purity, composition, and batch consistency while improving transparency and reproducibility.
Is the lowest-priced supplier always the best option?
No. Product quality, testing standards, analytical verification, and supplier reliability are generally more important than price alone.
How often should vendor comparisons be updated?
Pricing, laboratory reports, inventory availability, and supplier policies can change frequently and should be reviewed regularly.
Final Thoughts
VIP (Vasoactive Intestinal Peptide) remains one of the most extensively researched neuroimmune peptides because of its relationship with inflammation control, immune regulation, gastrointestinal physiology, pulmonary health, neuroprotection, vascular biology, and fibrosis-associated pathways. Ongoing investigations continue expanding scientific understanding of VIP's role in maintaining tissue homeostasis and regulating inflammatory responses across multiple organ systems.
When comparing VIP vendors, researchers should prioritize purity verification, third-party analytical testing, Certificate of Analysis availability, supplier reputation, and overall value rather than focusing exclusively on cost. A structured vendor-comparison process can help identify suppliers capable of meeting rigorous research-quality standards.
Current Research & Evidence
Research evidence for VIP has not yet been added.
Key Findings on VIP Use
Key findings for VIP have not yet been added.
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